Full Time Principal Investigator - Clinical Research

Summary

Our client is seeking a board-certified physician (MD or DO) to serve as a full-time Principal Investigator at a clinical research site in Plainview, New York.

This is an opportunity for a physician interested in building a career in clinical research. The site is part of an established clinical research network and benefits from standardized research processes, operational infrastructure, and dedicated recruitment and study coordination support.

The Principal Investigator will provide medical leadership and oversight for industry-sponsored clinical trials, primarily in cardiometabolic conditions, obesity and weight management, Type 2 Diabetes, pain, infectious diseases, and vaccines.

We welcome physicians with prior clinical research experience, as well as clinically experienced physicians who are interested in transitioning into research.

Key Responsibilities

Clinical Oversight and Participant Safety

• Serve as the Principal Investigator for assigned clinical trials, ensuring participant safety and appropriate medical oversight.
• Conduct medical evaluations, physical examinations, and clinical assessments throughout the course of research studies.
• Conduct medical history interviews during the pre-screening process to determine participant eligibility.
• Review medical histories, laboratory results, ECGs, and other clinical data to determine study eligibility and monitor participant safety.
• Oversee the informed consent process, ensuring participants understand study procedures, potential risks and benefits, and their rights.
• Assess, manage, document, and report adverse events and serious adverse events in accordance with applicable requirements.
• Make timely, independent medical decisions concerning participant eligibility, safety, and continued participation.

Research and Regulatory Oversight

• Ensure that studies are conducted in accordance with approved protocols, Good Clinical Practice (GCP), FDA regulations, and applicable ethical standards.
• Provide appropriate supervision of delegated clinical research activities and ensure accurate, timely medical documentation.
• Review and approve study-related clinical documentation and maintain appropriate investigator oversight.
• Participate in investigator meetings, sponsor visits, audits, inspections, and other research-related activities.
• Collaborate with study coordinators and site management to maintain research quality and protocol compliance.

Medical Leadership and Site Development

• Provide medical leadership, guidance, and training to research coordinators and other clinical team members.
• Collaborate with site leadership to support efficient study execution and the successful development of the research program.
• Participate in the evaluation of prospective clinical trials, including protocol feasibility and medical considerations.
• Help foster a collaborative, participant-centered culture emphasizing patient safety, scientific integrity, and high-quality research.

Qualifications

Required

• Doctor of Medicine (MD) or Doctor of Osteopathic Medicine (DO) degree.
• Completion of an accredited medical residency program in the United States.
• Board certification in Internal Medicine, Family Medicine, or another relevant specialty.
• Active, unrestricted New York State medical license.
• Experience providing direct clinical care to adult patients.
• Strong clinical judgment, attention to detail, and communication skills.
• Ability to work collaboratively with a multidisciplinary research team.
• Proficiency in professional written and spoken English.

Preferred

• Previous clinical research experience as a Principal Investigator, Sub-Investigator, or other physician investigator.
• Familiarity with FDA regulations, GCP principles, and industry-sponsored clinical trials.
• Clinical experience in cardiometabolic medicine, endocrinology, obesity medicine, infectious diseases, or other relevant therapeutic areas.

Schedule

This is a full-time, on-site position in Plainview, New York.

Normal business hours are approximately 8:30 AM to 5:30 PM, Monday through Friday. Occasional weekend availability may be required depending on study schedules.

Job Description

Our client is seeking a board-certified physician (MD or DO) to serve as a full-time Principal Investigator at a clinical research site in Plainview, New York.

This is an opportunity for a physician interested in building a career in clinical research. The site is part of an established clinical research network and benefits from standardized research processes, operational infrastructure, and dedicated recruitment and study coordination support.

The Principal Investigator will provide medical leadership and oversight for industry-sponsored clinical trials, primarily in cardiometabolic conditions, obesity and weight management, Type 2 Diabetes, pain, infectious diseases, and vaccines.

We welcome physicians with prior clinical research experience, as well as clinically experienced physicians who are interested in transitioning into research.

Key Responsibilities

Clinical Oversight and Participant Safety

• Serve as the Principal Investigator for assigned clinical trials, ensuring participant safety and appropriate medical oversight.
• Conduct medical evaluations, physical examinations, and clinical assessments throughout the course of research studies.
• Conduct medical history interviews during the pre-screening process to determine participant eligibility.
• Review medical histories, laboratory results, ECGs, and other clinical data to determine study eligibility and monitor participant safety.
• Oversee the informed consent process, ensuring participants understand study procedures, potential risks and benefits, and their rights.
• Assess, manage, document, and report adverse events and serious adverse events in accordance with applicable requirements.
• Make timely, independent medical decisions concerning participant eligibility, safety, and continued participation.

Research and Regulatory Oversight

• Ensure that studies are conducted in accordance with approved protocols, Good Clinical Practice (GCP), FDA regulations, and applicable ethical standards.
• Provide appropriate supervision of delegated clinical research activities and ensure accurate, timely medical documentation.
• Review and approve study-related clinical documentation and maintain appropriate investigator oversight.
• Participate in investigator meetings, sponsor visits, audits, inspections, and other research-related activities.
• Collaborate with study coordinators and site management to maintain research quality and protocol compliance.

Medical Leadership and Site Development

• Provide medical leadership, guidance, and training to research coordinators and other clinical team members.
• Collaborate with site leadership to support efficient study execution and the successful development of the research program.
• Participate in the evaluation of prospective clinical trials, including protocol feasibility and medical considerations.
• Help foster a collaborative, participant-centered culture emphasizing patient safety, scientific integrity, and high-quality research.

Qualifications

Required

• Doctor of Medicine (MD) or Doctor of Osteopathic Medicine (DO) degree.
• Completion of an accredited medical residency program in the United States.
• Board certification in Internal Medicine, Family Medicine, or another relevant specialty.
• Active, unrestricted New York State medical license.
• Experience providing direct clinical care to adult patients.
• Strong clinical judgment, attention to detail, and communication skills.
• Ability to work collaboratively with a multidisciplinary research team.
• Proficiency in professional written and spoken English.

Preferred

• Previous clinical research experience as a Principal Investigator, Sub-Investigator, or other physician investigator.
• Familiarity with FDA regulations, GCP principles, and industry-sponsored clinical trials.
• Clinical experience in cardiometabolic medicine, endocrinology, obesity medicine, infectious diseases, or other relevant therapeutic areas.

Schedule

This is a full-time, on-site position in Plainview, New York.

Normal business hours are approximately 8:30 AM to 5:30 PM, Monday through Friday. Occasional weekend availability may be required depending on study schedules.